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Updated: 2010-11-23 – 10:44
Keywords:cancer, treatment, sugar, mannose, improves
Cancer Cells – Archive
London, 23/11/2013 (People Online) – Some natural supplements such as mannose sugar may be of great help in treating cancer. According to a study funded by Cancer Research UK and Worldwide Cancer Research, published today in Nature, this nutritional supplement not only delays tumor growth but chemotherapy improves the effects of chemotherapy in several types of mice. cancer, highlights ABC.
It is known that tumors use more glucose than normal and healthy tissues. However, it is very difficult to control the amount of glucose in the body only with the diet. In this study, researchers have found that mannose may interfere with glucose to reduce the amount of sugar cells.
Professor Kevin Ryan, author of the Beatson UK Cancer Institute, said: "Many tumors need glucose to grow, limiting how much they can use, slowing down the development of cancer. The problem is that normal tissues need glucose, so we have found a mannose dose that can block enough glucose to delay tumor growth in mice, but not so much as to affect normal tissue.This is an initial study, but hopefully finding this perfect balance means that you can not in the future, mannose can be given to cancer patients to improve chemotherapy without harming their general health. "
The tumors require a lot of glucose to grow, so limiting how much they can use, slows down the formation of cancer.
In their study, researchers first looked at how mice responded to pancreatic, lung, or skin cancer when they used mannose to their drinking water and were given orally. It has been observed that addition of addition significantly reduced tumor growth and does not cause any side effects.
To investigate the effect of mannose on treating cancer, mice were treated with cisplatin and doxorubicin, the two most commonly used chemotherapy drugs. They have seen mannose improving the effects of chemotherapy, decreasing tumor growth, reducing tumor size, and even increasing the life of some mice.
Likewise, other cancers have been investigated, such as leukemia, osteosarcoma, ovarian cancer and intestines. The researchers bred the cancer cells in the laboratory and then treated mannose to convince them of their growth.
Some cells reacted well while others did not. It was also found that the presence of an enzyme that breaks down mannose in cells was a good indicator of the efficacy of the treatment.
Mannose is sometimes used for a short time to treat urinary tract infections, but its long-term effects have not been studied. It is important to carry out more research into the use of mannose before cancer patients.
In this sense, Martin Ledwick of Cancer Research UK believes that although these results are very promising for the future of cancer treatment, "this is a very early test and has not yet been tested on humans. Patients should not prescribe mannose alone it is important that you consult with your doctor before you dramatically change your diet or new supplements. "